(Mean±SD) | Group A (Cyclosporine+ Lubricant) |
Group B (Lubricant) |
Group C (Control) |
||||||
---|---|---|---|---|---|---|---|---|---|
- | Pre | 1 week | 3 months | Pre | 1 week | 3 months | Pre | 1 week | 3 months |
Tear osmolarity (mOsm/Lt) |
303.0±8.0 | 305.8±6.1 | 299.3± 10.6 | 299.4±10.8 | 309.4±13.2 | 302.8±13.5 | 303.1±12.8 | 310.1±10.0 | 310.1±14.7 |
p-value | 0.063 | 0.018 | 0.001 | 0.076 | 0.021 | 0.988 | |||
TBUT (sec) | 6.9 ± 2.5 | 6.6±2.8 | 8.7±3.5 | 6.5 ± 2.3 | 6.4±3.4 | 6.1±2.1 | 5.4 ± 2.9 | 5.0±2.6 | 4.4±2.6 |
p-value | 0.87 | 0.03 | 0.113 | 0.508 | 0.36 | 0.05 | |||
Schirmer’s 1 without anaesthesia (mm) | 17.4± 8.6 | 22.1±8.4 | 24.2±9.2 | 18.2± 8.9 | 18.2±8.5 | 21.7±9.3 | 13.4± 7.5 | 18.9±10.9 | 18.8±11.3 |
p-value | 0.04 | 0.087 | 0.58 | 0.369 | 0.55 | 0.57 | |||
Schirmer’s 1 with anaesthesia (mm) |
15.6 ± 8.5 | 16.9±6.9 | 19.2±9.0 | 14.2 ± 7.6 | 12.6±6.6 | 15.8±8.8 | 16.7 ± 8.4 | 15.8±8.9 | 15.4±10.9 |
p-value | 0.91 | 0.015 | 0.73 | 0.130 | 0.45 | 0.83 |