(Mean±SD) | Group A (Cyclosporine+Lubricant) |
Group B (Lubricant) |
Group C (Control) |
|||||
---|---|---|---|---|---|---|---|---|
- | Pre | 3 months | Pre | 3 months | Pre | 3 months | ||
Tear osmolarity(mosm/lt) | 303.0±8.0 | 299.3± 10.6 | 299.4±10.8 | 302.8±13.5 | 303.1±12.8 | 310.1±14.7 | ||
p-value | 0.256 | 0.364 | 0.876 | |||||
TBUT (sec) | 6.9±2.5 | 8.7±3.5 | 6.5±2.3 | 6.1±2.1 | 5.4±2.9 | 4.4±2.6 | ||
p-value | 0.023 | 0.226 | 0.036 | |||||
Schirmer’s 1 without anaesthesia (mm) | 17.4±8.6 | 24.2±9.2 | 18.2±8.9 | 21.7±9.3 | 13.4±7.5 | 18.8±11.3 | ||
p-value | 0.004 | 0.909 | 0.431 | |||||
Schirmer’s 1 with anaesthesia (mm) |
15.6±8.5 | 19.2±9.0 | 14.2±7.6 | 15.8±8.8 | 16.7±8.4 | 15.4±10.9 | ||
p-value | 0.068 | 0.198 | 0.313 | |||||
Subjective Questionnaire (Total score=24) |
11.41 ±2.2 | 8.35±2.15 | 10.08 ±1.20 | 10.61±2.14 | 11.70±1.40 | 14.50±2.20 | ||
p-value | 0.031 | 0.451 | 0.050 |