Table 4: Multivariable Adjusted* 2-Year Incident Odds Ratios and 95% CI of Stroke, Stratified by AMD-Type and Age Group

All Age Group Age Group
65-69 70-74 75-79 ≥ 80
Combined Stroke (n=89,501)
Non-AMD 1.00 1.00 1.00 1.00 1.00
All AMD 1.21 (1.18, 1.23) 1.15 (1.06, 1.24) 1.16 (1.10, 1.22) 1.20 (1.15, 1.25) 1.20 (1.17, 1.24)
Non-neovascular AMD 1.18 (1.15, 1.21) 1.06 (0.96, 1.16) 1.14 (1.08, 1.22) 1.19 (1.13, 1.24) 1.18 (1.15, 1.22)
Neovascular AMD 1.31 (1.26, 1.36) 1.50 (1.28, 1.75) 1.22 (1.09, 1.36) 1.24 (1.14, 1.35) 1.30 (1.23, 1.37)
Ischemic Stroke (n=80,018)
All AMD 1.20 (1.18, 1.23) 1.14 (1.05, 1.24) 1.15 (1.09, 1.22) 1.21 (1.16, 1.26) 1.20 (1.16, 1.23)
Non-neovascular AMD 1.18 (1.15, 1.20) 1.05 (0.95, 1.16) 1.14 (1.07, 1.21) 1.20 (1.14, 1.26) 1.17 (1.14, 1.21)
Neovascular AMD 1.31 (1.26, 1.37) 1.49 (1.26, 1.75) 1.22 (1.08, 1.38) 1.25 (1.14, 1.37) 1.29 (1.22, 1.37)
Hemorrhagic Stroke (n=7,048)
All AMD 1.23 (1.15, 1.32) 1.26 (0.94, 1.63) 1.20 (0.99, 1.44) 1.17 (1.01, 1.35) 1.23 (1.13, 1.35)
Non-neovascular AMD 1.22 (1.14, 1.32) 1.19 (0.86, 1.60) 1.15 (0.93, 1.42) 1.17 (1.00, 1.37) 1.24 (1.12, 1.36)
Neovascular AMD 1.26 (1.10, 1.45) 1.53 (0.84, 2.54) 1.38 (0.92, 1.98) 1.16 (0.85, 1.55) 1.21 (1.00, 1.45)

* Adjusted for age within each age group, gender, race, hypertension, and diabetes. Persons without AMD during the baseline period comprised the referent group.
CI: Confidence Interval; AMD: Age-related Macular Degeneration.