No |
Age |
Gender |
Clinical Findings |
Treatment Prior to Excision |
Risk Factors |
Proposed Pathogenic Sequence |
Tumor Location |
1 |
79 |
f |
Chronic conjunctivitis |
Cromoglycic acid |
None |
Primary CIN? |
Limbus, 16x6x4mm |
2 |
67 |
m |
Conjunctivitis |
None |
None |
Primary CIN? |
Nasal and temporal limbus |
3 |
39 |
m |
Red eye |
Vit A ointment |
None |
Primary CIN? |
Temporal limbus |
4 |
73 |
m |
Corneal neoplasia |
None |
None |
Possibly primary CIN developing from a pinguecula |
Corneal at the limbus, adjacent to pinguecula |
5 |
61 |
m |
Corneal neoplasia |
None |
None |
Primary CIN? |
Medial limbus with corneal part (2-3mm) 10x5x2mm |
6 |
64 |
m |
At least 4 years ocular surface problems with circular pannus |
Topical steroids, antiviral ointment |
HPV 16 |
Malignant transformation due to HPV 16 |
Limbus with corneal part at 7 and 12h |
7 |
67 |
m |
"Pterygium" since at least 3 years with unusual extension |
None |
None |
Primary CIN mimicking pterygium or CIN developing from altered epithelium of a pterygium |
Medial limbus with corneal part (2mm) |
8 |
56 |
f |
Atypical Pterygium with whitish plaque and vascularisation |
None |
HPV 16 |
Malignant transformation due to HPV 16 |
Limbus, 11x7x1mm |
9 |
61 |
m |
Red eye |
None |
None |
Primary CIN? |
Medial limbus with corneal part (2mm) |
10 |
53 |
m |
Superficial vascularisation onto the cornea |
None |
Explosion injury 30 years previously |
DNA-damage due to the trauma and malignant transformation during repair phase |
Limbus with corneal part (2mm) |
11 |
29 |
m |
Whitish neoplasia |
1991 tectonic keratoplasty due to malignancy, 1992 rekeratoplasty due to corneal melting |
Xeroderma pigmentosum, UV-B radiation |
DNA-damage and malignant transformation due to UV-B radiation and defective repair mechanisms |
Limbus with corneal part (4mm) 4x4x2 |
12 |
67 |
m |
Red eye |
Dexpanthenol eye drops |
None |
Primary CIN? |
Medial limbus |