| Parameter/IRD Type |
USH II |
USH I |
STD |
RP |
MD |
CD |
CRD |
CHRD |
CACD |
BBD |
Normal Controls |
Kruskal-Wallis-Test (Chi2 Test) |
| Rod b-wave amplitude, µV |
nd |
nd |
124.67 (15.88; 189.9) |
109.37 (19.24; 199.5) |
166.295 (92.8; 300) |
208.41 (128.8; 273.2) |
79.92 (15.88; 130.2) |
46.155 (25.95; 66.36) |
100.67 (81.22; 115.7) |
nd |
292.93 (163.667; 435.602) |
p=0.0001*
|
| Rod b-wave implicit time, ms |
nd |
nd |
98 (67.2; 131.5) |
101.25 (88; 114.5) |
103.5 (19; 121) |
60.8 (17; 94) |
104.75 (76; 111) |
65.5 (65; 66) |
91.9 (62; 106.5) |
nd |
84 (58.1; 97.1) |
p=0.0097*
|
| Maximum a-wave amplitude, µV |
nd |
nd |
200.445 (64.82; 370.7) |
81.155 (8.469; 254.8) |
206.9 (199.95; 236.8) |
137.75 (38.529; 220. 729) |
63.44 (25.33; 193.5) |
47.61 (21.84; 73.51) |
132.15 (53.34; 174.68) |
33.14 (27.22; 39.06) |
227.07 (106.6; 322.2) |
p=0.0001*
|
| Maximum a-wave implicit time, ms |
nd |
nd |
16.5 (15; 23) |
16.3 (12; 24) |
16.3 (15.5; 17) |
17. 75 (15; 23.5) |
23.5 (15.5; 24.5) |
21 (16; 25) |
18 (17; 19.5) |
2.4 (2.4; 2.6) |
16 (15.5; 17) |
p=0.004*
|
| Maximum b-wave amplitude, µV |
nd |
nd |
352.05 (97.9; 763.3) |
177.42 (21.78; 467.6) |
416.5
(292; 531.71) |
292.4 (35.915; 412.361) |
131.96 (14.32; 271.678) |
90.08 (27.58; 108.9) |
288.575 (140.3; 369) |
55.32 (16.4; 94.2) |
415.185 (277.15; 640.05) |
p=0.0001*
|
| Maximum b- wave implicit time, ms |
nd |
nd |
48 (34.4; 63) |
55.5 (51; 84) |
49 (41.6; 53.5) |
50.5 (35.32; 59.95) |
48 (37.6; 78.5) |
56 (40; 61) |
42.7 (40; 59) |
56.5 (46.4; 66.6) |
46 (42.25; 55.75) |
p=0.2221 |
| OP amplitude, µV |
nd |
nd |
42.53 (7.99; 109) |
13.64 (6.48;
40.62) |
40.6 (28.03; 80) |
41.6
(37.6; 59) |
17.315 (11.43; 40.13) |
6 (3.716; 16.52) |
34.54 (33.95; 35.41) |
nd |
78.83
(65.59; 95.06) |
p=0.0001*
|
| OP implicit time, ms |
nd |
nd |
23.6 (22.4; 29.2) |
24 (23.5; 28.8) |
24.4 (23; 24.8) |
24.5 (23.6; 25.5) |
25.4 (23.2; 32) |
25.5 (24.8; 29) |
25.6 (24.8; 27.5) |
nd |
23.6 (22.5; 24.7) |
p=0.0012*
|
| Photopic a- wave amplitude, µV |
nd |
nd |
25.27 (8.623; 79.37) |
21.53 (2.618; 41.56) |
41.24 (25.53; 104.8) |
22.455 (4.058; 63.68) |
10.355 (0.4; 21.35) |
12.442 (4.771;
27.49) |
11.35 (10.06; 12.64) |
nd |
39.18 (15.81; 61.45) |
p=0.0001*
|
| Photopic a- wave implicit time, ms |
nd |
nd |
15.5 (14.5; 30.4) |
17
(15; 70.44) |
15.5 (15; 30.5) |
16 (15; 18.41) |
19.75
(15; 31.5) |
12.442 (4.771; 27.49) |
15.75 (15; 16.5) |
19.74 (10; 46.94) |
14
(12.25; 16) |
p=0.0001*
|
| Photopic b-wave amplitude, µV |
nd |
16.09 (13.23; 26.16) |
110.645 (12.829; 225.8605) |
24.39 (6.1; 172.7) |
147.36 (110.4; 214.55) |
66.435 (6.43; 141.4) |
30.59 (7.587; 68.97) |
19.82 (2.771; 58.12) |
97.1 (45.14; 137.89) |
19.74
(10; 46.94) |
171.13 (79.41; 271.38) |
p=0.0001*
|
| Photopic b- wave implicit tim, ms |
nd |
33.6 (31.2; 37.2) |
31.2 (27.1; 41.33) |
38.4 (29; 59) |
30.5 (26.2; 59.4) |
32.75 (29.4; 42.58) |
38 (17.85;
74.4) |
35.4 (30; 43.9) |
31 (30.6;
34.2) |
48.8 (42.8; 49.8) |
30 (28; 33) |
p=0.0001*
|
| 30 Hz flicker wave amplitude, µV |
44.47 (16.64; 72.3) |
6.93 (5.47; 8.45) |
65.515 (24.88; 179.456) |
10.82 (2.22; 103) |
90.81 (57.48; 111.6) |
32.83 (4.54; 108.51) |
22.19 (2.812; 67.5) |
16.64 (3.12; 39.17) |
54.09 (25.45; 104.62) |
18.185 (9.12; 20) |
101.41 (59.676; 136.958) |
p=0.0001*
|
| 30 Hz flicker implicit time, ms |
32 (30; 72.6) |
62.4 (60; 62.4) |
60.5 (47.4; 73.2) |
68.9 (45; 78) |
59.5 (58.2; 61) |
64.5 (52.6; 75.9) |
69 (60; 75) |
71.4 (30.5; 75.5) |
62.4 (61.8; 65) |
75.9 (65; 76.8) |
59 (48.3; 61.85) |
p=0.0001*
|
nd- not detectable
* -indicates that the difference was found to be statistically significant
5th and 95th quantiles are indicated in brackets
Kruskal-Wallis test (Chi2-test for more than 2 groups) was used for the comparison of IRD subgroups and with subjects with normal ophthalmological finding.