| Presence of LCs (% of Positivity of LCs) |
SSDE |
NSSDE |
NDE |
P Value |
| Central cornea |
1 |
55.55 |
29.41 |
35.71 |
|
| 2 |
100 |
88.23 |
92.85 |
| 3 |
77.77 |
41.17 |
50 |
| Peripheral cornea |
1 |
66.66 |
35.29 |
57.14 |
| 2 |
100 |
88.23 |
100 |
| 3 |
83.33 |
47.05 |
64.28 |
| LCs Density in Each Corneal Section (Cell/mm2) |
| Central cornea |
1 (median) |
25 |
0 |
0 |
SSDE and NSSDE vs NDE 0.0833 |
| 1 (range) |
0-126 |
0-50 |
0-31 |
| 2 (median) |
79 |
44 |
22 |
SSDE and NSSDE vs NDE0.0098 SSDE vs NDE 0.0031 |
| 2 (range) |
13-371 |
0-392 |
0-63 |
| 3 (median) |
38 |
0 |
3 |
SSDE and NSSDE vs NDE0.0130 SSDE vs NDE 0.0169 |
| 3 (range) |
0-201 |
0-76 |
0-44 |
| Peripheral cornea |
1 (median) |
34,5 |
0 |
16 |
SSDE and NSSDE vs NDE0.2343 |
| 1 (range) |
0-107 |
0-164 |
0-44 |
| 2 (median) |
119.5 |
88 |
82 |
SSDE and NSSDE vs NDE0.0791 |
| 2 (range) |
25-398 |
0-541 |
6-258 |
| 3 (median) |
50 |
0 |
22 |
SSDE and NSSDE vs NDE0.0791 |
| 3 (range) |
0-189 |
0-157 |
0-101 |
| Mean LCs Density in Each Corneal Area (Cell/mm2) |
| Central cornea (median) |
|
56.66 |
29.33 |
14.66 |
SSDE and NSSDE vs NDE 0.0061 |
| Central cornea (range) |
|
4.33-165.33 |
0-130.66 |
0-42 |
| Peripheral cornea (median) |
|
58.83 |
58.66 |
44 |
SSDE and NSSDE vs NDE0.1032 |
| Peripheral cornea (range) |
|
21-159.33 |
0-220 |
2-119.33 |
| |
|
P between central and peripheral 0.4859 (Wilcoxon test) |
P between central and peripheral 0.0605 (Wilcoxon test) |
P between central and peripheral 0.0019 (Wilcoxon test) |
|
1. Intermediate epithelial cell layers
2. Sub-basal nerve plexus
3. Sub-epithelial nerve plexus
LCs: Langherans Cells; SSDE:Sjögren Syndrome Dry Eye; NSSDE: Non Sjögren Syndrome Dry Eye; NDE: Non Dry Eye.