Table 1: Method of Grading Healing of Bone Defects

Gross Points Awarded
Defect open; unhealed
Defect unhealed, filled with fibrous tissue or unaltered graft material
Defect filled with new bone; less than 25%
Defect filled with new bone to 50%
Defect filled with new bone 50 to 75%
Defect filled with new bone 75% or more
Defect completely filled; indistinguishable from surrounding bone
0
0
5
10
15
20
25
Radiographic
Defined clearly visible; unfilled
Defined clearly visible; filled with clearly recognizable graft particles
Defect partially filled; less than 25%
Defect filled to 50%
Defect filled over 50%
Defect filled with new bone, with trabecular bridging and unrecognizable host-graft interface
Defect indistinguishable from surrounding tissue

0
0
5
10
15
20
25
Histomorphometry
No new bone present
Unaltered graft material occupied over 50% of defect
Graft particles surrounded by thin rims of new bone
Particles replaced by new lamellar bone with many particles still visible
Over one half particles replaced with new lamellar bone; revascularization evident
Dense bone trabeculae present with moderate osteogenesis; some endochondral bone formation or direct ossification
Cavity filled with newly formed bone trabeculae lined with osteoblasts; bone marrow formation

0
10
20
20
30
40
50
Maximum score 100