Table 1: Continuous variables for the training and validation cohort showing statistical differences in distribution between the two cohorts in Mann-Whitney-Wilcox test except for age and neutrophil count. This did not differ when the variables where categorized as described.

- Training cohort
(2009-2013)
n=140		 Test cohort
(2003-2008)
n = 130		 - -
Variable - - Missing
(%)		 - Missing
(%)		 Mann-Whitney-Wilcoxon test Chi2 test
Age at surgery (years) Mean 64.7 0 63.7 0 0.531 N/A
- Median 65.0 - 64.0 - - -
- Range 21 - 90 - 30 - 85 - - -
Hemoglobin Mean 7.1 0 7.4 1 *0.007 *0.030
(mmol/L) Median 7.1 - 7.5 - - -
- Range 4.8 - 9.8 - 5.0 - 9.7 - - -
C-reactive protein Mean 48.1 - 68.5 15 *0.018 *0.038
(mg/L) Median 21.0 - 37.0 - - -
- Range 1 - 329 4 0 - 266 - - -
Neutrophil count Mean 6.8 16 6.7 32 0.757 1
(x 10^9/L) Median 5.6 - 5.8 - - -
- Range 0.2 - 25.1 - 1.5 - 18.0 - - -
Alkaline phosphase Mean 182.5 16 289.6 9 *0.006 *0.031
(U/L) Median 122.0 - 158.0 - - -
- Range 39.0 - 796.0 - 49.0 - 2520.0 - - -
Days from diagnose
to surgery		 Mean 1468 0 1113 0 *<0.001 *0.004
- - - - - - -
(Days) Median 667.6 - 152.5 - - -
- Range 0 - 10610 - 0 -31180 - - -