Fig. (1) Graphical illustration of operation procedure. (a) Placement of guide wires perpendicular to the one surface and insertion of guide wires. (b) Cannulation of bone defect using cannulated drill bit. (c). Guide wires parallel to the drill hole cut off at the surface of the bone. (d). Insertion of the CMC-C compound with or without Colloss E. (e). Closing of wound with sutures in both periost and skin.