Patients with Osteoarthritis in all Three Knee Compartments and Patients with Medial Knee Osteoarthritis Have a Phenotype with High Bone Mass and High Fat Mass but Proportionally Low Lean Mass

Table 4: Odds ratio for having osteoarthritis (OA) in all knee compartments or localized medial OA of the knee.

		All		Women		Men
Parameter		OA in all Compartments	Medial OA	OA in all Compartments	Medial OA	OA in all Compartments	Medial OA
For Each SD Higher
	BMI	2. 4 (1.7, 3.3) *	2.4 (1.9, 3.2) *	2.9 (1.8, 4.5) *	3.7 (2.1, 6.4) *	1.9 (1.2, 3.1) *	2.2 (1.6, 3.1) *
	Total body BMD	1.8 (1.1, 3.0) *	2.6 (1.8, 3.8) *	4.2 (1.8, 9.7) *	3.5 (1.6, 7.8) *	0.9 (0.5, 1.8)	2.3 (1.5, 3.5) *
	Absolute fat mass	1.6 (1.03, 2.4) *	2.7 (2.0, 3.7) *	2.1 (1.2, 3.7) *	4.2 (2.2, 8.1) *	1.0 (0.5, 2.0)	2.6 (1.7, 3.8) *
	Proportion fat mass	1.6 (0.98, 2.7)	3.2 (2.2, 4.7) *	2.3 (1.1, 4.7) *	5.1 (2.1, 12.1) *	1.0 (0.5, 2.2)	3.0 (1.9, 4.8) *
For Each SD Lower
	Absolute lean mass	1.2 (0.7, 1.9)	0.8 (0.6, 1.02)	1.1 (0.6, 2.0)	0.3 (0.2, 0.7) *	1.2 (0.6, 2.6)	1.0 (0.7, 1.6)
	Proportion lean mass	2.1 (1.2, 3.5) *	4.7 (3.0, 7.3) *	2.4 (1.2, 4.8) *	5.3 (2.2, 12.8) *	1.6 (0.7, 3.6)	5.0 (2.8, 9.1) *

BMD = bone mineral density; BMI= body mass index; data presented as means with 95% CI in brackets; 95% CI for odds ratio were calculated by logistic regression; *Statistical significant differences.