Fig. (3) These graphs show percentages of Nav 1.8-IR neurons in small sized (<600µm²), medium sized (600-1200µm²) and large sized neurons (>1200µm²). There were significant differences between puncture and sham groups, and puncture and naïve groups in small neurons at Day 1. There were no significant differences in medium and large sized neurons. There were no significant differences among three groups at Day 7. * p<0.05 compared with naïve group, + p<0.05 compared sham group.