Table 1: Demographic characteristics and biochemical parameters of the study population.
|
Control Subjects |
Obese and Overweight Subjects |
Diabetic Subjects |
N (male/female) |
23(9/14) |
35 (7/28) |
31(10/21) |
Age (years) |
39±9 |
40 ±13** |
41± 9 b**b |
weight (kg) |
63.77±3 |
83.43±5* |
93.19±6* |
BMI (kg/m2) |
22.65 ±1.7 |
32.98 ± 5.06* |
35.25 ± 4.33*a |
HbA1c (%) |
4.9±2.2 |
5.3±0.77** |
7.2±0.8a*a |
Insulin (µU / ml) |
6.15±0.93 |
10.82 ± 4.59* |
11.1 ± 5.25 b* |
Glucose (mg/dl) |
95.6±5.5 |
100 ± 10.5** |
191.7± 61.8a * |
HOMA-IR |
1.45±0.28 |
2.66 ± 1.15* |
5.14 ± 2.45a* |
Obestatin (ng/ml) |
12.38±3.74 |
7.76 ± 2.09* |
6.35 ± 2.48a* |
Data presented as mean ± standard deviation. BMI, body mass index; HOMA-IR, homeostasis model assessment –insulin resistance index. * P<0.05, ** P>0.05 compared with control group. a P<0.05, b P>0.05 compared with obese subjects.