|
REGIMEN SWITCH N=610 (24.8%) N(%) or Median(IQR) |
NO REGIMEN SWITCH N=1847 (75.2%) N(%) or Median(IQR) |
UNIVARIATE ODDS RATIO (95% CI) |
P- VALUE |
MULTIVARIATE ODDS RATIO (95% CI) |
P- VALUE |
|
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Age(years) | 34 (10.0) | 34 (11.0) | 1.00 (0.99,1.01) | 0.444 | 0.98 (0.96,0.99) | 0.0006 |
| Gender(%Female) | 64 (10.5%) | 158 (8.1%) | 1.35 (0.99,1.83) | 0.0594 | ||
| Marital Status(%Married) |
156 (30.6%) | 182 (29.8%) | 0.93 (0.76,1.13) | 0.4685 | ||
| Race/Ethnicity | 0.0012 | |||||
| Caucasian | 271 (44.4%) | 769 (41.6%) | referent | referent | ||
| African-American | 231 (37.9%) | 821 (44.5%) | 0.80 (0.65,0.98) | 0.0283 | 0.76 (0.6,0.98) | 0.0332 |
| Hispanic | 63 (10.3%) | 168 (9.1%) | 1.06 (0.77,1.47) | 0.7043 | 1.22 (0.84,1.77) | 0.3018 |
| Other | 45 (7.4%) | 89 (4.8%) | 1.44 (0.98,2.11) | 0.0654 | 1.77 (1.11,2.83) | 0.0165 |
| Rank Status | ||||||
| Officer/Warrant | 53 (8.7%) | 185 (10.0%) | 0.92 (0.66,1.26) | 0.5873 | ||
| Enlisted | 468 (76.7%) | 1494 (80.9%) | referent | |||
| Duty Status | ||||||
| Active | 495 (81.1%) | 1573 (85.2%) | referent | |||
| Retired | 29 (4.8%) | 88 (4.8%) | 1.05 (0.68,1.61) | 0.834 | ||
| Dependent | 46 (7.5%) | 88 (4.8%) | 1.66 (1.15,2.41) | 0.0072 | ||
| Other | 40 (6.6%) | 98 (5.3%) | 1.3 (0.89,1.9) | 0.1813 | ||
| Site | ||||||
| NMCP | 37 (6.1%) | 140 (7.6%) | 0.76 (0.52,1.12) | 0.1711 | ||
| NMCSD | 92 (15.1%) | 264 (14.3%) | 1.01 (0.77,1.32) | 0.9607 | ||
| SAMMC | 183 (30.0%) | 553 (29.9%) | 0.96 (0.77,1.18) | 0.6812 | ||
| TAMC | 9 (1.5%) | 55 (3.0%) | 0.47 (0.23,0.97) | 0.0407 | ||
| WRNMMC | 289 (47.4%) | 835 (45.2%) | referent | |||
| HIV Related | ||||||
| HIV Diagnosis to HAART initiation (months) | 52 (98.2) | 29 (75.6) | 1.003 (1.001,1.005) | <.0001 | ||
| Viral load at HAART Initiation (log copies/ml) | 0.0271 | |||||
| <400 | 34 (5.6%) | 188 (10.2%) | referent | referent | ||
| 400-<1000 | 47 (7.7%) | 189 (10.2%) | 1.38 (0.85,2.23) | 0.1983 | 1.06 (0.61,1.86) | 0.8287 |
| 1000-<10000 | 131 (21.5%) | 343 (18.6%) | 2.11 (1.39,3.21) | 0.0004 | 1.82 (1.13,2.94) | 0.0138 |
| >=10000 | 381 (62.5%) | 1047 (56.7%) | 2.01 (1.37,2.95) | 0.0004 | 1.67 (1.07,2.6) | 0.0241 |
| Missing | 17 (2.8%) | 80 (4.3%) | ||||
| CD4 Cell Count at HAART initiation (cells/ml) | 0.0001 | |||||
| <200 | 203 (33.3%) | 306 (16.6%) | 2.65 (2.1,3.34) | <.0001 | 1.94 (1.43,2.63) | <.0001 |
| 200-<350 | 165 (27.0%) | 567 (30.7%) | 1.16 (0.93,1.46) | 0.1964 | 1.14 (0.88,1.49) | 0.3289 |
| >=350 | 216 (35.4%) | 863 (46.7%) | referent | referent | ||
| Missing | 26 (4.3%) | 111 (6.0%) | ||||
| ARV Prior to HAART (%) | 365 (59.8%) | 748 (40.5%) | 2.19 (1.82,2.64) | <.0001 | 2.06 (1.63,2.62) | <.0001 |
| Period of HAART Initiation | ||||||
| 1996-2001 | 466 (76.4%) | 1142 (61.8%) | 2.46 (1.8,3.35) | <.0001 | ||
| 2002-2007 | 91 (14.9%) | 386 (20.9%) | 1.42 (0.98,2.05) | 0.0636 | ||
| 2008-2012 | 53 (8.7%) | 319 (17.3%) | referent | |||
| Comorbidities | ||||||
| Malignancy other than Basal Cell Carcinoma | 100 (16.4%) | 173 (9.4%) | 1.90 (1.46,2.47) | <.0001 | ||
| Diabetes Mellitus | 68 (11.1%) | 133 (7.2%) | 1.62 (1.19,2.20) | 0.0022 | ||
| Anxiety Disorder | 71 (11.6%) | 144 (7.8%) | 1.56 (1.15,2.10) | 0.0038 | ||
| Major Depression | 196 (32.1%) | 398 (21.5%) | 1.72 (1.41,2.11) | <.0001 | 1.48 (1.15,1.9) | 0.0023 |
| Substance Abuse | 85 (13.9%) | 198 (10.7%) | 1.35 (1.03,1.77) | 0.0315 | ||
| Serum Levels at HAART Initiation | ||||||
| ALT(U/L) | 34 (26.0) | 32 (23.0) | 1.00 (1.00,1.00) | 0.1366 | ||
| Creatinine (mg/dL) | 1 (0.2) | 1 (0.2) | 0.79 (0.50,1.24) | 0.3023 | ||
| Hemoglobin(g/dL) | 14 (2.1) | 14 (1.7) | 0.85 (0.79,0.91) | <.0001 | 0.9 (0.83,0.97) | 0.0048 |