| TOTAL COHORT N(%) or Median(IQR) N=2457 |
CAUCASIAN N(%) or Median(IQR) N=1040 |
AFRICAN-AMERICAN N(%) or Median (IQR) N=1052 |
HISPANIC N(%) or Median(IQR) N=231 |
OTHER N(%) or Median(IQR) N=134 |
P-VALUE | |
|---|---|---|---|---|---|---|
| Prior Medical Illnesses | ||||||
| Cerebrovascular Disease | 15 (0.6%) | 8 (0.8%) | 4 (0.4%) | 2 (0.9%) | 1 (0.7%) | 0.6504 |
| Chronic Obstructive Pulmonary Disease | 27 (1.1%) | 18 (1.7%) | 6 (0.6%) | 1 (0.4%) | 2 (1.5%) | 0.0536 |
| Chronic Viral Hepatitis Disease | 274 (11.2%) | 104 (10.0%) | 134 (12.7%) | 24 (10.4%) | 12 (9.0%) | 0.1831 |
| Cirrhosis | 25 (1.0%) | 13 (1.3%) | 7 (0.7%) | 4 (1.7%) | 1 (0.7%) | 0.3734 |
| Coronary Artery Disease | 71 (2.9%) | 46 (4.4%) | 16 (1.5%) | 7 (3.0%) | 2 (1.5%) | 0.0008 |
| Diabetes Mellitus | 201 (8.2%) | 82 (7.9%) | 92 (8.7%) | 19 (8.2%) | 8 (6.0%) | 0.6962 |
| Malignancy other than Basal Cell Carcinoma | 273 (11.1%) | 171 (16.4%) | 81 (7.7%) | 12 (5.2%) | 9 (6.7%) | <.0001 |
| Tuberculosis other than latent infection | 37 (1.5%) | 8 (0.8%) | 19 (1.8%) | 6 (2.6%) | 4 (3.0%) | 0.0406 |
| Prior Mental Health Illnesses | ||||||
| Anxiety Disorder | 215 (8.8%) | 128 (12.3%) | 50 (4.8%) | 24 (10.4%) | 13 (9.7%) | <.0001 |
| Bipolar Disorder | 48 (2.0%) | 22 (2.1%) | 21 (2.0%) | 3 (1.3%) | 2 (1.5%) | 0.8451 |
| Major Depression | 594 (24.2%) | 274 (26.3%) | 225 (21.4%) | 56 (24.2%) | 39 (29.1%) | 0.0305 |
| Obsessive-Compulsive Disorder | 3 (0.1%) | 1 (0.1%) | 1 (0.4%) | 1 (0.7%) | 0.0588 | |
| Post-Traumatic Stress Disorder | 37 (1.5%) | 13 (1.3%) | 13 (1.2%) | 6 (2.6%) | 5 (3.7%) | 0.0627 |
| Prior Suicide Attempt | 23 (0.9%) | 7 (0.7%) | 5 (0.5%) | 7 (3.0%) | 4 (3.0%) | 0.0002 |
| Schizophrenia | 5 (0.2%) | 2 (0.2%) | 2 (0.2%) | 1 (0.7%) | 0.488 | |
| Substance Abuse | 283 (11.5%) | 135 (13.0%) | 104 (9.9%) | 31 (13.4%) | 13 (9.7%) | 0.1029 |
| Serum Levels at Initiation | ||||||
| ALT(U/L) | 32 (25) | 32 (25) | 32 (23) | 35 (28) | 32 (23) | 0.0001 |
| AST(U/L) | 30 (16) | 28 (13) | 32 (18) | 31 (18) | 29 (14) | <.0001 |
| Total Bilirubin (mg/dL) | 0.6 (0.4) | 0.6 (0.4) | 0.6 (0.3) | 0.6 (0.4) | 0.6 (0.4) | <.0001 |
| HDL (mg/dL) | 39 (15) | 37 (14) | 43 (14) | 37 (15) | 37 (12) | 0.0389 |
| LDL (mg/dL) | 100 (39) | 99 (41) | 105 (41) | 97 (32) | 100 (44) | <.0001 |
| Triglycerides (mg/dL) | 114 (98) | 135 (119) | 98 (75) | 132 (114) | 110.5 (68) | 0.4518 |
| Glucose (mg/dL) | 87 (17) | 87 (18) | 86 (16) | 87 (15) | 87 (13) | <.0001 |
| Creatinine (mg/dL) | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.3) | 0.9 (0.3) | 0.9 (0.3) | <.0001 |
| Hemoglobin(g/dL) | 14.3 (1.9) | 14.6 (1.8) | 13.9 (1.8) | 14.7 (1.7) | 14.8 (1.8) | 0.0001 |