Table 1: Summarizing patient demographics, clinical findings and treatment outcomes between subgroups. All values are median [inter-quartile range] unless otherwise stated. Legend: SpAD – Spondyloarthritis or associated disease, AI – Other autoimmune disease, iLVV – idiopathic large vessel vasculitis, CRP – C-reactive Protein, ESR – Erythrocyte sedimentation rate, PET-CT – Positron-emission Tomography, SUV – standard uptake value, MRI – magnetic resonance imaging.

iLVV SpAD AI p-value
Patient Demographics
n 33 16 13
Female, n (%) 26 (79%) 11 (69%) 11 (85%) 0.58
Never Smoker, n (%) 14 (42%) 6 (38%) 3 (23%) 0.41
Age at Diagnosis, yrs 70.3 [59.3-73.3] 59.2 [54.0-63.8] 68.1 [58.7-72.3] 0.01
Follow-up, mts 11 [3-36] 38 [18-63] 39 [7-52] 0.01
Clinical Features
Fever, n (%) 7 (21%) 7 (44%) 4 (31%) 0.22
Weight loss, n (%) 21 (64%) 8 (50%) 7 (54%) 0.73
Night Sweats, n (%) 16 (48%) 9 (56%) 6 (46%) 0.71
Myalgia, n (%) 22 (67%) 9 (56%) 7 (54%) 0.70
Headache, n (%) 18 (55%) 8 (50%) 4 (31%) 0.34
Jaw claudication, n (%) 10 (30%) 2 (13%) 3 (23%) 0.44
Symptom Duration, d 92 [53-203] 97 [38-201] 79 [53-181] 0.91
Laboratory Parameters
Leucocytes, Tsd/µl 8.8 [7.8-10.0] 9.1 [8.2-10.7] 10.6 [7.5-11.0] 0.73
CRP, mg/l 90 [50-120] 73 [37-118] 107 [31-149] 0.67
ESR, mm/hr 76 [69-93] 79 [58-88] 81 [62-100] 0.90
Imaging 0.46
PET-CT, n (%) 21 (64%) 7 (44%) 8 (62%)
- SUVmax 4.4 [3.2-6.0] 3.1 [2.9-3.2] 3.5 [3.3-4.7] 0.305
MRI, n (%) 8 (24%) 6 (38%) 3 (23%)
Site affected
- Ascending Thoracic Aorta, n (%) 24 (83%) 12 (92%) 6 (55%) 0.05
- Descending Thoracic Aorta, n (%) 27 (93%) 10 (77%) 9 (82%) 0.21
- Abdominal Aorta, n (%) 26 (90%) 8 (62%) 8 (73%) 0.08
- Other large vessel, n (%) 20 (69%) 7 (54%) 6 (55%) 0.43
No. of Sites affected
- Single site, n (%) 4 (14%) 1 (8%) 4 (36%) 0.14
- ≥3 Sites, n (%) 23 (79%) 8 (62%) 6 (55%) 0.24
Treatment 0.39
Standard Protocol, n (%) 22 (67%) 13 (81%) 10 (77%)
Steroids only, n (%) 11 (33%) 3 (19%) 3 (23%)
Outcomes
Relapsing Patients, n (%) 12 (36%) 8 (50%) 6 (46%) 0.62
Refractory Disease, n (%) 2 (6%) 5 (31%) 3 (23%) 0.05