|
|
|
iLVV |
SpAD |
AI |
p-value |
Patient Demographics |
|
|
|
|
|
n |
|
33 |
16 |
13 |
|
|
Female, n (%) |
|
26 |
(79%) |
11 |
(69%) |
11 |
(85%) |
0.58 |
|
Never Smoker, n (%) |
14 |
(42%) |
6 |
(38%) |
3 |
(23%) |
0.41 |
|
Age at Diagnosis, yrs |
70.3 |
[59.3-73.3] |
59.2 |
[54.0-63.8] |
68.1 |
[58.7-72.3] |
0.01 |
|
Follow-up, mts |
11 |
[3-36] |
38 |
[18-63] |
39 |
[7-52] |
0.01 |
Clinical Features |
|
|
|
|
|
|
|
|
Fever, n (%) |
|
7 |
(21%) |
7 |
(44%) |
4 |
(31%) |
0.22 |
|
Weight loss, n (%) |
21 |
(64%) |
8 |
(50%) |
7 |
(54%) |
0.73 |
|
Night Sweats, n (%) |
16 |
(48%) |
9 |
(56%) |
6 |
(46%) |
0.71 |
|
Myalgia, n (%) |
|
22 |
(67%) |
9 |
(56%) |
7 |
(54%) |
0.70 |
|
Headache, n (%) |
18 |
(55%) |
8 |
(50%) |
4 |
(31%) |
0.34 |
|
Jaw claudication, n (%) |
10 |
(30%) |
2 |
(13%) |
3 |
(23%) |
0.44 |
|
Symptom Duration, d |
92 |
[53-203] |
97 |
[38-201] |
79 |
[53-181] |
0.91 |
Laboratory Parameters |
|
|
|
|
|
|
|
Leucocytes, Tsd/µl |
8.8 |
[7.8-10.0] |
9.1 |
[8.2-10.7] |
10.6 |
[7.5-11.0] |
0.73 |
|
CRP, mg/l |
|
90 |
[50-120] |
73 |
[37-118] |
107 |
[31-149] |
0.67 |
|
ESR, mm/hr |
|
76 |
[69-93] |
79 |
[58-88] |
81 |
[62-100] |
0.90 |
Imaging |
|
|
|
|
|
|
|
0.46 |
|
PET-CT, n (%) |
21 |
(64%) |
7 |
(44%) |
8 |
(62%) |
|
|
- SUVmax
|
|
4.4 |
[3.2-6.0] |
3.1 |
[2.9-3.2] |
3.5 |
[3.3-4.7] |
0.305 |
|
MRI, n (%) |
|
8 |
(24%) |
6 |
(38%) |
3 |
(23%) |
|
|
Site affected |
|
|
|
|
|
|
|
|
|
- Ascending Thoracic Aorta, n (%) |
24 |
(83%) |
12 |
(92%) |
6 |
(55%) |
0.05 |
|
- Descending Thoracic Aorta, n (%) |
27 |
(93%) |
10 |
(77%) |
9 |
(82%) |
0.21 |
|
- Abdominal Aorta, n (%) |
26 |
(90%) |
8 |
(62%) |
8 |
(73%) |
0.08 |
|
- Other large vessel, n (%) |
20 |
(69%) |
7 |
(54%) |
6 |
(55%) |
0.43 |
|
No. of Sites affected |
|
|
|
|
|
|
|
|
- Single site, n (%) |
4 |
(14%) |
1 |
(8%) |
4 |
(36%) |
0.14 |
|
- ≥3 Sites, n (%) |
23 |
(79%) |
8 |
(62%) |
6 |
(55%) |
0.24 |
Treatment |
|
|
|
|
|
|
|
0.39 |
|
Standard Protocol, n (%) |
22 |
(67%) |
13 |
(81%) |
10 |
(77%) |
|
|
Steroids only, n (%) |
11 |
(33%) |
3 |
(19%) |
3 |
(23%) |
|
Outcomes |
|
|
|
|
|
|
|
|
|
Relapsing Patients, n (%) |
12 |
(36%) |
8 |
(50%) |
6 |
(46%) |
0.62 |
|
Refractory Disease, n (%) |
2 |
(6%) |
5 |
(31%) |
3 |
(23%) |
0.05 |