Table 1: Patient-reported outcome measures.

Patient-Reported Outcome Measure	Description
12-item Short-Form Health Survey, version 2 (SF-12)	A 12-item measure of health status with 8 domains (physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, mental health) and Physical and Mental Component Summary scores (0 to 100 scale, higher scores indicate better outcomes) [36]
Brief Pain Inventory-Short Form (BPI-SF)	An 11-item measure of pain severity (Pain Severity Index 4 items: worst, least, average, current; 0 to 10 scale, higher scores indicate more severe pain) and pain interference with function (Pain Interference Index 7 items: general activity, mood, walking ability, normal work, relations with other people, sleep, enjoyment of life; 0 to 10 scale, higher scores indicate more interference) [32]
EuroQol 5 dimensions, 3 levels (EQ-5D)	A 5-item measure of general health status that assesses mobility, self-care, performance of usual activities, pain or discomfort, and anxiety or depression. Using the United States–based scoring, the health state utility is scored on a -0.11 to 1.00 scale (higher scores indicate better health status) [31]
Fibromyalgia Impact Questionnaire-revised (FIQ-R)	A 21-item measure of function, overall impact of fibromyalgia, and intensity of symptoms over the past 7 days. Overall Score based on 0 to 100 scale, function on 0 to 90 scale, overall impact on 0 to 20 scale, and symptom intensity on 0 to 100 scale (higher scores indicate greater impact of fibromyalgia) [34] Note: at Follow-up this measure was administered to patients who were re-diagnosed with fibromyalgia by the physician at the Follow-up site visit.
London Fibromyalgia Epidemiology Study Screening Questionnaire (LFESSQ)	A 6-item screening tool to assess the presence of chronic widespread pain. Patients screened positive based on responses to the 4 pain items (LFESSQ-4) indicating bilateral pain, above and below the waist, lasting at least 1 week in the past 3 months [28]
Medical Outcomes Study Sleep Scale (MOS-SS)	A 12-item measure of sleep outcomes that includes 6 dimensions (sleep disturbance, snoring, shortness of breath, sleep adequacy, sleep somnolence, sleep quantity). Nine items make up the Overall Sleep Problems Index; 0 to 100 scale, higher scores indicate more sleep problems except for sleep adequacy and sleep quantity items, where higher scores indicate better sleep outcomes) [35]
Modified (self-report) American College of Rheumatology 2010 Criteria (ACR 2010)	A 3-item measure of pain locations and symptoms; 0 to 31 scale (higher scores indicate worse outcomes) comprised of the widespread pain index (0 to 19 scale) and symptom severity (0 to 12 scale) subscales [33]
Work Productivity and Activity Impairment (WPAI) Questionnaire	A 6-item measure used to quantify Overall Work Impairment, comprised of absenteeism and presenteeism, and Activity Impairment with scores expressed as impairment percentages (higher scores indicate more productivity loss and greater impairment) [37]