Table 1: Demographic and baseline characteristics of patients who entered the extension.

Etanercept + Methotrexate
(n=260)
DMARD + Methotrexate
(n=126)
Demographic and Baseline Characteristics
Age, mean (SD), y 48.4 (11.8) 48.4 (11.2)
Female, n (%) 227 (87.3) 115 (91.3)
Ethnicitya
   White, n (%) 120 (46.2) 55 (43.7)
   Mestizos, n (%) 57 (21.9) 32 (25.4)
   African-Latin American, n (%) 36 (13.8) 22 (17.5)
   Other, n (%) 47 (18.1) 17 (13.5)
Body mass index, (kg/m2) mean (SD) 26.4 (4.9) 27.3 (5.0)
Prior tobacco use, n (%) 63 (24.2) 30 (23.8)
Baseline Disease Characteristics
Disease duration, mean (SD), y 7.8 (6.9) 9.0 (7.7)
C-reactive protein (mg/L), mean (SD) 21.4 (26.1) 20.4 (21.9)
Rheumatoid factor positive, n (%) 227 (87.3) 104 (82.5)
Cyclic citrulinated peptide antibody positive, n (%) 232 (89.2) 107 (84.9)
Erythrocyte sedimentation rate (mm/h), mean (SD) 43.1 (16.6) 42.7 (16.1)
DAS28 (ESR), mean (SD) 6.6 (0.8) 6.7 (0.8)
Tender joint count, mean (SD)b 25.3 (11.8) 27.1 (12.6)
Swollen joint count, mean (SD)b 18.4 (8.5) 19.8 (10.5)
Physician global assessment (1–10), mean (SD) 6.7 (1.6) 6.7 (1.6)
Duration of morning stiffness, min, mean (SD) 182.5 (265.4) 142.7 (149.6)
Prior Medication Use
Prior methotrexate use, n (%) 260 (100.0) 126 (100.0)
Prior NSAID use, n (%) 216 (83.1) 110 (87.3)
Prior corticosteroid use, n (%) 194 (74.6) 93 (73.8)
Baseline Patient-Reported Characteristics
Total HAQ disability index, mean (SD) 1.6 (0.7) 1.6 (0.7)
Subject global assessment (1–10), mean (SD) 7.1 (2.0) 7.2 (1.9)
VAS general health (0–100 mm), mean (SD) 59.7 (21.4) 61.6 (20.5)
VAS pain (0–100 mm), mean (SD) 64.9 (21.2) 64.9 (21.5)
VAS fatigue (0–100 mm), mean (SD) 55.7 (26.0) 58.1 (25.6)
SF-36 PCS, mean (SD) 30.4 (7.2) 30.1 (6.8)
SF-36 MCS, mean (SD) 40.2 (11.1) 39.7 (10.1)
SF-36 vitality domain score, mean (SD) 12.3 (3.8) 12.2 (3.8)

DAS-28 indicates disease activity Score in 28 joints; DMARD, disease-modifying anti-rheumatic drug; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; MCS, mental component summary; NSAID, nonsteroidal anti-inflammatory drug; PCS, physical component summary; SD, standard deviation; SF-36-item, short form health survey; VAS, visual analog scale.
a Case report forms included Asian and Mulatto ethnicities as options, but no patients selected these options.
b Values for tender and swollen joint counts are prorated.