The Correlation of Muscle Biopsy Scores with the Clinical Variables in Idiopathic Inflammatory Myopathies

Table 3: Muscle biopsy scores of patients with IIM.

Biopsy score, IQR (Q1,Q3)	Group 1	Group 2	Group 3	Group 4	p-value
Prior CS (N=70)	(n=23)	(n=8)	(n=4)	(n=35)
After CS (N=25)	(n=5)	(n=1)	(n=1)	(n=18)
Inflammation
Prior CS	1.0 (0, 3.0)	0 (0, 0.7)	0.5 (0, 1.0)	0 (0, 1.0)	0.218
After CS	0 (0, 4.0)	0	4.0	1.5 (0, 3)	0.382
Vasculitis
Prior CS	0 (0, 0)	0 (0, 0.2.2)	0 (0, 0)	0 (0, 0)	0.465
After CS	0 (0, 0)	0	0	0 (0, 0)	0.943
Muscle
Atrophy
Prior CS	1.0 (1.0, 2.0)	1.5 (1.0, 3.7)	1.5 (0.2, 2.7)	2.0 (1.0, 2.0)	0.947
After CS	1.0 (0.5, 2.0)	6.0	2.0	2.0 (1.0, 2.0)	0.196
Degenerative
Prior CS	1.0 (0, 2. 0)	0 (0, 1.0)	0 (0, 2.2)	0 (0, 1.0)	0.031*
After CS	1.0 (0, 1. 0)	2.0	2.0	1.0 (0, 1.0)	0.184
Invaded non-necrotic fiber
Prior CS	0 (0, 0)	0 (0, 0)	0 (0, 0)	0 (0, 0)	0.685
After CS	0 (0, 0)	0	0	0 (0, 0)	0.736
Endomysial fibrosis
Prior CS	1.0 (0, 2.0)	0 (0, 1.7)	0.5 (0, 1.0)	0 (0, 1.0)	0.017*
After CS	1(0, 1.5)	0	0	1.0 (0, 1.0)	0.549
Total muscle biopsy score
Prior CS	3 (2, 5)	2.5 (1.0, 5.7)	1.5 (0.2, 5.7)	2.0 (1.0, 3.0)	0.113
After CS	3.0 (0.5, 4.0)	9.0	5	3.0 (2.0, 3.2)	0.334

p-value is from the Kruskal–Wallis test.
*p<0.05
Prior CS=underwent biopsy prior using corticosteroid; After CS= underwent biopsy after using corticosteroid.