Table 1: Patient demographics at baseline (ITT population).

SC group (n=235) IC group (n=381) Total (N=616)
n % n % N %
Sex 235 100 381 100 616 100
Male 99 42.1 139 36.5 238 38.6
Female 136 57.9 242 63.5 378 61.4
Age, years 232 98.7 380 99.7 612 99.4
<60 73 31.5 121 31.8 194 31.7
60–70 68 29.3 99 26.1 167 27.3
70–80 72 31.0 114 30.0 186 30.4
>80 19 8.2 46 12.1 65 10.6
BMI (kg/m2) 229 97.4 364 95.5 593 96.3
Underweight (<20) 1 0.4 6 1.6 7 1.2
Normal (≥20 to <25) 58 25.3 102 28.0 160 27.0
Overweight (≥25 to <30) 111 48.5 172 47.3 283 47.7
Obese (≥30 to <40) 53 23.1 76 20.9 129 21.8
Severely obese (≥40) 6 2.6 8 2.2 14 2.4
Knee OA location 232 98.7 375 98.4 607 98.5
Right 128 55.2 185 49.3 313 51.6
Left 79 34.1 162 43.2 241 39.7
Bilateral 25 10.8 28 7.5 53 8.7
Knee OA duration, years 232 98.7 375 98.4 607 98.5
<1 29 12.4 118 31.1 147 24.0
1-5 98 42.1 145 38.3 243 39.7
5-10 72 30.9 75 19.8 147 24.0
>10 34 14.6 41 10.8 75 12.3
Knee OA severity (Kellgren-Lawrence grade) 235 100 381 100 616 100
I 23 9.8 31 8.1 54 8.8
II 108 46.0 147 38.6 255 41.4
III 104 44.3 203 53.3 307 49.8

BMI body mass index; OA osteoarthritis.