Table 1: Baseline demographic and clinical characteristics.

Baseline Characteristics Total
(n=314)
ETN
(n=156)
IFX
(n=32)
ETN VS. IFX
P-Value
ADA
(n=126)
ETN VS. ADA
P-value
Age (years), mean (SD) 56.3 (12.6) 55.5 (12.1) 59.4 (14.8) 0.111 56.6 (12.6) 0.458
Min, median, max 21.0, 56.0, 90.0 21.0, 54.5, 84.0 24.0, 59.5, 82.0 25.0, 56.5, 90.0
Female, n (%) 241 (76.8) 122 (78.2) 26 (81.3) 0.816 93 (73.8) 0.402
RA duration (years), mean (SD) 9.0 (4.9) 9.3 (4.7) 8.1 (2.6) 0.124 8.9 (5.5) 0.615
Quan-Charlson comorbidity score1, mean (SD) 0.1 (0.5) 0.1 (0.5) 0.2 (0.6) 0.344 0.1 (0.5) 0.870
Prior 3-month DMARD use, n (%)
None 79 (25.2) 47 (30.1) 8 (25.0) 0.672 24 (19.1) 0.039
One 95 (30.3) 46 (29.5) 14 (43.8) 0.145 35 (27.8) 0.792
More than one 140 (44.6) 63 (40.4) 10 (31.3) 0.427 67 (53.2) 0.041
Initiation of anti-TNF, n (%)
Monotherapy 72 (22.9) 43 (27.6) 8 (25.0) 0.831 21 (16.7) 0.033
Concomitant DMARD 242 (77.1) 113 (72.4) 24 (75.0) 0.831 105 (83.3) 0.033
Medication insurance, n (%)
Government 159 (50.6) 78 (50.0) 15 (46.9) 0.847 66 (52.4) 0.720
Private 125 (39.8) 60 (38.5) 15 (46.9) 0.430 50 (39.7) 0.902
None 12 (3.8) 8 (5.1) 1 (3.1) 1.000 3 (2.4) 0.356
Not government, but unknown if private or none 4 (1.3) 1 (0.6) 0 (0.00) 1.000 3 (2.4) 0.328
Unknown 14 (4.5) 9 (5.8) 1 (3.1) 1.000 4 (3.2) 0.396

1The updated Quan-Charlson comorbidity index score is based on 12 conditions. ETN=Etanercept, IFX=Infliximab, ADA=Adalimumab