Table 3: Personal experience of various aspects of using the SB4 pre-filled pen – by previous treatment and overall (Full Analysis Set).

- Naïve to bDMARDs Switch from another pen to SB4 pen Switch from syringe to SB4 pen Other bDMARD therapy Total
- (N=331) (N=93) (N=59) (N=9) (N=492)
Aspect n (missing) (%) n (missing) (%) n (missing) (%) n (missing) (%) n (missing) (%)
Ease of execution of the injection (‘simple’ or ‘very simple’) 296 (89%) 84 (90%) 50 (1) (86%) 9 (100%) 439 (1) (89%)
Holding the pre-filled pen (‘simple’ or ‘very simple’) 294 (6) (90%) 84 (90%) 46 (78%) 8 (89%) 432 (6) (89%)
Duration of the injection (‘satisfied’ or ‘very satisfied’) 271 (1) (82%) 75 (1) (82%) 48 (2) (84%) 8 (89%) 402 (4) (82%)
Injection without add. pressing of a button (‘satisfied’ or ‘very satisfied’) 293 (5) (90%) 75 (1) (82%) 48 (1) (83%) 8 (89%) 424 (7) (87%)
Acoustic signal (click) (‘clear’ or ‘very clear’) 303 (2) (92%) 82 (88%) 51 (1) (88%) 9 (100%) 445 (3) (91%)
Indication of completed injection (‘clear’ or ‘very clear’) 292 (1) (88%) 78 (84%) 50 (85%) 9 (100%) 429 (1) (87%)
Surface feeling (‘comfortable’ or ‘very comfortable’) 259 (2) (79%) 70 (1) (76%) 40 (1) (69%) 6 (67%) 375 (4) (77%)
Weight (‘comfortable’ or ‘very comfortable’) 268 (6) (82%) 78 (1) (85%) 42 (3) (75%) 6 (67%) 394 (10) (82%)
Satisfaction in comparison with the previous application system for bDMARDS (‘satisfied’ or ‘very satisfied’) NA 79 (1) (86%) 52 (1) (90%) 5 (2) (71%) 136 (4) (87%)a

bDMARD = Biological Disease-Modifying Antirheumatic Drug.
a 331 patients naïve to bDMARDs not included in calculations.