Table 1: Clinical and Laboratory Parameters After One Cycle of Rituximab (RTX) with Ongoing Etanercept Treatment: DAS28, IgG, IgA, IgM and Rheumatoid Factor (RF); Values Below the Normal Range are Grey (Values in % Compared to the Starting Level)

Patient 1
Months after RTX 0 3 6 9 15 45
DAS28 5,7 4,4 4,4 4,8 3,5 2,13
IgG (690-1600 mg/dl) 884 835 (94) 671 (76) 690 (78) 909 (103) 877 (99)
IgA (70-370 mg/dl) 283 250 (88) 197 (70) 210 (74) 244 (86) 301 (106)
IgM (40-240 mg/dl) 138 104 (75) 72 (52) 87 (63) 76 (55) 91 (66)
RF (U/l) 267 139 (52) 127 (48) 62 (23) 54 (20) 123 (46)
Patient 2
Months after RTX 0 3 6 9 12 45
DAS28 5 3,9 3,3 2,58 2,44 2,78
IgG (690-1600 mg/dl) 1100 1180 (107) 1100 (100) 1100 (100) 1200 (109) 1345 (122)
IgA (70-370 mg/dl) 228 260 (114) 246 (108) 261 (114) 300 (130) 309 (135)
IgM (40-240 mg/dl) 66 59 (90) 49 (79) 59 (90) 53 (80) 48 (76)
RF (U/l) 174 131 (75) 107 (61) 103 (59) 136 (78) 172 (99)