Table 6a: Physical Function: Treatment Effects Relative to Placebo

95% CrI Probability that Treatment Shows Small, Moderate or Large Improvement Relative to Placebo*
Treatment (mg) ES** Low High Small Moderate Large
acetaminophen 4000 -0.04 -0.20 0.13 0.03 0 0
nsNSAIDs
naproxen 1000 -0.37 -0.51 -0.23 0.99 0.04 0.00
ibuprofen 2400 -0.41 -0.64 -0.18 0.96 0.22 0.00
diclofenac 150 -0.52 -0.70 -0.33 >0.99 0.58 0.00
COX-2 selective NSAIDs
celecoxib 100 -0.15 -0.35 0.06 0.30 0.00 0.00
celecoxib 200 -0.34 -0.42 -0.27 >0.99 0.00 0.00
celecoxib 400 -0.26 -0.43 -0.09 0.74 0.00 0.00
lumiracoxib 100 -0.32 -0.48 -0.15 0.92 0.02 0.00
lumiracoxib 200 -0.35 -0.52 -0.17 0.95 0.04 0.00
lumiracoxib 400 -0.36 -0.53 -0.20 0.97 0.05 0.00
etoricoxib 30 -0.61 -0.76 -0.46 >0.99 0.93 0.01
etoricoxib 60 -0.64 -0.83 -0.46 >0.99 0.93 0.05

* Small (ES ≥ 0.2), moderate (ES ≥ 0.5) or large (ES ≥ 0.8).
** Negative effect sizes indicate improvement.