Fig. (2) Correlations of S-PEN with Kallman radiographic scores in HOA: (A) baseline, (B) after two years. The shown graphs were constructed from the data without adjustment to age and disease duration. Abbreviations: S-PEN/TP = serum pentosidine levels normalised to the levels of total serum protein; HOA = hand osteoarthritis; r = Spearman correlation coefficient; p = statistical significance.