Table 2: Clinical Characteristics of PFAPA Patients with Variants in the MEFV Gene Compared with those of PFAPA Patients without MEFV Variants

Patients with MEFV Variants (n=13) Patients without MEFV Variants (n=7) P Value
Age at onset (years) 2.8±1.9 3.2±1.9 NS
Age at Diagnosis (years) 4.3±2.2 4.9±1.9 NS
Male: female ratio 5/8 4/3 NS
Family history of PFAPA 4/9 3/4 NS
Attack duration (days) 3.6±0.86 5.3±1.89 P=0.0174
Interval between attacks (weeks) 4.9±1.59 5.5±0.96 NS
Cyclic periodic attacks 5/13 4/7 NS
Pharyngitis 13/13 7/7 NS
Aphthae 7/13 5/7 NS
Enlarged tonsillitis 13/13 7/7 NS
Abdominal pains 1/13 2/7 NS
Musculoskeletal Pains 1/13 2/7 NS
Headaches 4/13 5/7 NS
WBC/L 143±41 142±41 NS
ESR mm/h 87±23 72±14 NS
CRP levels mg/dL 6.52±3.53 5.87±2.85 NS

NS: not significant.