| N | Average Age ± SD | % Women | Lifestyle | Affected Joint | Exclusion Criteria | Blinded Assessment | Patients Groups | Assessment | Results | |
|---|---|---|---|---|---|---|---|---|---|---|
| Messier (2004) [23] | 316 | 69.0 ± 0.8 | 74% | independent | Knee | MMS < 24 | Yes | -control (education) -diet+exercise (DE) -diet (D) -exercise (E) |
18 months | ↓ pain (DE)* ↑function (DE)* |
| Miller (2006) [24] | 87 | 69.7 ± 0.6 | 64.9% | independent | Knee | Pathologies CI exercise | Yes | -control (education) -diet+exercise |
6 months | ↓ pain * ↑function* |