| Parameter | Finnish 1977-92 |
Spain 1994-2007 |
French 1985-2009 |
Swedish 1984-2004 |
Chinese 1985-2006 |
Present Study 2004-2011 |
|---|---|---|---|---|---|---|
| Number of Patients | 110 | 1010 | 445 | 205 | 573 | 332¶ |
| Classification Criteria Used | Californian/ European Community |
European Community | AECG | AECG | AECG | AECG ACR |
| Number of Centres | 1 | 10 | 2 | 1 | 1 | 1 |
| Mean age (yrs) | 62±13a | 53.0±0.48 | 53.6±14 | 39 | 44.5±10.6 | |
| Disease duration(mo) | 74.9±4 | 62.65±65.67 | ||||
| Female:Male | 35.7:1 | 13:1 | 8.9:1 | 10.7:1 | 18.5:1 | |
| Arthralgia/arthritis | 106 (97) | 640 (63) | 222 (50) | (76) | 274 (47.8) | 275 (82.8) |
| Raynaud’s | 55 (50) | 187 (18) | 189 (42) | (20) | 101 (17.6) | 1 (0.3) |
| Pulmonary | 33 (31)b | 112 (11) | 55 (12) | 38 (19) | 221/522 (42.3) | 40 (12.1) |
| Renal | 48 (5) | 34 (8) | 78 (38) | 192 (33.5) | 49 (14.75) | |
| GI/hepatobiliary | 5 (0.5)c | 26 (12)d | 188 (32.8) | 29 (8.73) | ||
| Neurological | 35 (32) | 131 (13) | 70 (16) | 68 (11.9) | 32 (9.64) | |
| Vasculitis | 91 (9) | 70 (16) | 40 (12) | |||
| Positive LSG biopsy | 77 (70) | 449/561 (79) | 403 (92%) | 303/334 (90.7) | 287/306 (93.8) | |
| Subjective oral sicca | 97 (88) | 975 (96) | 380 (86)e | 484 (84.5) | 313/332 (94.3) | |
| Subjective ophthalmic sicca | 86 (72) | 968 (96) | 371 (83.4)e | 401 (70) | 295/332 (88.9) | |
| ANA | (83) g | 859/1005 (85)f | 347 (78)g | 101/170 (59) | 474/565 (83.9) | 206/312 (66) g |
| RF | (74) | 467/982 (48) | 184 (41) | 292/476 (61.3) | 180/301 (59.8) | |
| Anti-Ro | 518/1002 (52) | 221 (48) | (61)h | 474/568 (83.5) | 148/232 (63.8) | |
| Anti-La | 343/1000 (34) | 139 (31) | (41.5)h | 231/568 (40.7) | 88/231 (38.1) | |
| Cryoglobulinemia | 62/628 (10) | 68 (15) | 0/69 | |||
| Hyperglobulinemia | 225 (50) | 50/261 (15.4) | ||||
| Follow up (months) | 108 (1.2-216) | 76.1±51 | 31±29 |