Table 3.: Odds ratios (95% CI) in multivariate analysis of associations of being in remission at the 5year follow-up and DAS28 at inclusion, HAQ at inclusion or pain at inclusion, controlled for group (group 1 – included in 1990s, group 2 – included in 2000s), gender, age, smoking habits, disease duration and RF. DAS28, HAQ and pain were analysed separate due to high correlation.

  DAS28 HAQ Pain
OR (95% CI) p-Value OR (95% CI) p-Value OR (95% CI) p-Value
Group 1 1   1   1  
2 1.756 (1.414-2.180) <0.001 1.749 (1.408-2.173) <0.001 1.705 (1.380-2.106) <0.001
Gender Women 1   1   1  
Men 2.652 (2.107-3.339) <0.001 2.527 (2.000-3.191) <0.001 2.630 (2.099-3.294) <0.001
Age   0.988 (0.981-0.995) 0.001 0.987 (0.979-0.994) <0.001 0.985 (0.978-0.996) <0.001
Smoking Non 1   1   1  
Smoker 0.739 (0.567-0.964) 0.026 0.813 (0.623-1.061) 0.127 0.777 (0.599-1.007) 0.057
Previous 0.946 (0.734-1.219) 0.669 0.961 (0.744-1.240) 0.757 0.947 (0.739-1.213) 0.664
Duration   0.941 (0.908-0.976) 0.001 0.953 (0.919-0.98) 0.009 0.956 (0.923-0.990) 0.012
RF negative 1   1   1  
positive 0.615 (0.494-0.766) <0.001 0.593 (0.476-0.739) <0.001 0.638 (0.515-0.790) <0.001
DAS28   0.658 (0.601-0.721) <0.001        
HAQ       0.593 (0.496-0.709) <0.001    
Pain           0.991 (0.987-0.996) <0.001