Neglected Respiratory Toxicity Caused by Cancer Therapy

Table 1: Assessment of Link Between Agent and Event^*

	Definite	Probable	Possible	Conditional
Appropriate temporal sequence	Yes	Yes	Yes	Yes
Known reaction to agent	Yes	Yes	Yes	No
Improved with dechallenge¹	Yes	Yes	Yes-No	No
Relapse on rechallenge²	Yes	?	?	?
Event reasonably explained by clicinal state or other therapies	No	No	Yes	No

*Modified from Karch and Lasagna [⁷].

¹The effects of stopping the drug or reducing the dose.

²Relapse of the effects after restarting the drug.