Table 4: Ventilation effectiveness according to blood gas analysis parameters in COPD and OHS.
|
Before NIV |
With NIV |
Diff. |
95% CI of the difference |
|
|
mean |
SE |
mean |
SE |
mean |
lower |
upper |
p |
COPD |
|
|
|
|
|
|
|
|
pH |
7.36 |
0.06 |
7.45 |
0.04 |
-0.09 |
-0.11 |
-0.07 |
0 |
pCO2
|
8.7 |
1.5 |
5.8 |
0.8 |
2.83 |
2.34 |
3.29 |
0 |
pO2
|
8.0 |
1.8 |
10.2 |
1.4 |
-2.25 |
-2.94 |
-1.56 |
0 |
HCO3
|
32.4 |
6.0 |
30.2 |
3.7 |
2.24 |
0.67 |
3.80 |
0.006 |
BE |
8.6 |
5.2 |
5.8 |
3.0 |
2.78 |
1.30 |
4.26 |
0 |
SO2
|
87.5 |
8.2 |
95.7 |
2.6 |
-8.2 |
-10.64 |
-5.75 |
0 |
6-MWT |
206.8 |
110.4 |
267.0 |
108.4 |
60.2 |
81.7 |
38.8 |
0 |
OHS |
|
|
|
|
|
|
|
|
pH |
7.37 |
0.06 |
7.45 |
0.05 |
-0.08 |
-0.10 |
-0.06 |
0 |
pCO2
|
8.5 |
1.2 |
5.9 |
0.8 |
2.55 |
2.12 |
2.98 |
0 |
pO2
|
7.6 |
1.3 |
10.0 |
1.7 |
-2.37 |
-2.99 |
-1.75 |
0 |
HCO3
|
32.7 |
4.9 |
30.0 |
4.0 |
2.65 |
0.98 |
4.32 |
0.003 |
BE |
8.5 |
4.1 |
5.1 |
2.7 |
3.43 |
2.02 |
4.84 |
0 |
SO2
|
86.7 |
5.4 |
95.1 |
2.6 |
-8.34 |
-10.40 |
-6.35 |
0 |
6-MWT |
190.8 |
124.0 |
259.0 |
137.4 |
65 |
93.7 |
36.2 |
0 |
Blood gas analysis at rest, spontaneous breathing.
Before NIV: Before initiation of ventilation; with NIV: before discharge with ventilation.
Values as mean, standard deviation, and difference: before NIV – with NIV; 6-MWT walk distance: with NIV – before NIV.
p: significance level, two-sided, (t-test for dependent samples).