Table 3.: Exercise Parameters and Tests on Inspiratory Muscle Strength on Study Phase 2

  HEET 1 NIV HEET 2
I II III IV V
TwPmo [kPa] 1.64 ± 0.40 1.43 ± 0.65 1.91 ± 0.65 1.79 ± 0.63 1.59 ± 0.68
TwPes [kPa] 1.43 ± 0.42 1.24 ± 0.60 1.63 ± 0.60 1.63 ± 0.61 1.45 ± 0.60
TwPga [kPa] -1.20 ± 0.43 -1.10 ± 0.38 -1.14 ± 0.34 -1.16 ± 0.36 -1.01 ± 0.40
TwPdi [kPa] 2.49 ± 0.62 2.22 ± 0.78 2.63 ± 0.85 2.69 ± 0.83 2.37 ± 0.87
PImax [kPa] 12.0 ± 1.9 12.5 ± 1.7 12.2 ± 1.4 12.1 ± 1.7 12.5 ± 1.1
HR [min-1] 71 ± 12 184 ± 9 65 ± 9 67 ± 8 187 ± 9
BL [mg/dl] 1.6 ± 0.4 11.2 ± 1.6 3.7 ± 1.5 2.3 ± 0.7 9.8 ± 2.2
PaO2 [mmHg] 82.9 ± 7.4 99.9 ± 14.5 86.3 ± 17.7 83.0 ± 14.0 89.3 ± 12.0
PaCO2 [mmHg] 37.8 ± 3.2 31.1 ± 4.4 30.6 ± 7.4 30.1 ± 6.9 30.1 ± 2.3
pH   7.41 ± 0.02 7.23 ± 0.03 7.45 ± 0.06 7.49 ± 0.07 7.25 ± 0.05

BL = blood lactate; HEET = heavy-intensity exercise testing; HR = heart rate; NIV = non-invasive ventilation; PaCO2 = partial pressure of carbon dioxide; PaO2 = partial pressure of oxygen; PImax = maximal inspiratory pressure; TwPdi = twitch transdiaphragmatic pressure; TwPes = twitch esophageal pressure; TwPga = twitch gastric pressure; TwPmo = twitch mouth pressure.