| Smokers | Non-Smokers | |||||
|---|---|---|---|---|---|---|
| Budesonide (n= 15 ) | Budesonide + Formoterol (n= 14 ) | p | Budesonide (n= 14 ) | Budesonide + Formoterol (n= 14 ) | p | |
| Cells in Sputum | ||||||
| Total cells (x 106/g) | 1.8 (0.4-20.0) | 2.5 (0.4-11.6) | 0.74 | 2.5 (0.6-14.4) | 3.1 (0.2-31.0) | 0.45 |
| Eosinophils (x 106/g) % | 0 (0-0.5) 2.3 (0-16.2) |
0 (0-0.1) 0.6 (0-5.3) |
0.63 0.16 |
0 (0-0.4) 0.8 (0-8.0) |
0 (0-1.1) 1.6 (0-4.0) |
0.43 0.56 |
| Neutrophils (x 106/g) % | 0.7 (0.1-18.7) 29.0 (8.0-93.3) |
1.0 (0-10.4) 51.5 (4.5-90.3) |
0.45 0.52 |
0.3 (0-6.9) 14.8 (2.5-76) |
1.2 (0-16.2) 29.9 (11-85) |
0.01 0.12 |
| Macrophages (x 106/g) % | 1.2 (0.2-2.9) 63.3 (4.5-83.3) |
1.5 (0.4-2.0) 44.8 (8.3-88.0) |
0.50 0.61 |
1.5 (0.4-7.0) 81.0 (15.3-94.0) |
1.7 (0.2-25.9) 64.5 (12.5-86.5) |
0.37 0.23 |
| Lymphocytes (x 106/g) % | 0 (0-0.1) 1.3 (0-4.5) |
0 (0-0.1) 0.6 (0-3.0) |
0.85 0.30 |
0 (0-0.3) 1.4 (0-7.3) |
0.1 (0-0.2) 1.8 (0-2.8) |
0.65 0.74 |
| ECP (ng/ml) | 41 (19- 459) | 54 (7-3851) | 0.74 | 122 (5-370) n=8 |
158 (40-1462) n=8 |
0.52 |
| MPO (ng/ml) | 187 (7-997) | 163 (11-7674) | 0.58 | 103 (3-856) n=8 |
36 (4-3879) n=9 |
0.49 |