Table 1: Summary of Epidemiological Studies on Sleep Deprivation and Diabetes Mellitus

First Author Year Sample Study Duration Comments
Chaput et al. [135] 2007 740 3 years Sleeping < 6 hours led to impaired glucose tolerance.
Mallonet al. [136] 2005 2663 12 years Difficulties maintaining sleep or short sleep duration are associated with increased incidence of diabetes in men.
Nilsson et al. [137] 2004 6599 14.8 ± 2.4 years Sleep disturbances increased risk of diabetes.
Tuomilehto et al. [138] 2008 2800 2 years Short (≤6 hours) or long ≥8h) sleep duration increased risk of type 2 diabetes in middle-aged women but not in men.
Meisinger et al. [139] 2005 8300 11 years Difficulty maintaining sleep was associated with an increased risk of type 2 diabetes in men and women.
Hayashino et al.[140] 2007 6509 6 years Difficulty initiating sleep was associated with higher risks of diabetes in relatively healthy adults.
Kawakami et al. [141] 2004 2649 8 years Sleep disturbances associated with 2-3 higher risk of diabetes.
Choi et al. [142] 2008 4222 1 year Both short and long sleep durations was related to increased risk of the metabolic syndrome.
Gangwisch et al. [143] 2007 8992 10 years Short sleep duration could be a significant risk factor for diabetes.
Xu et al. [145] 2010 10143 10 years Day napping and short night sleeping was associated with diabetes.
Rafalson et al. [146] 2010 1455 6 years Short sleep duration was associated with elevated risk of impaired fasting glucose, mediated via insulin resistance.
Yaggi et al. [147] 2006 1709 18 years Short and long sleep durations increase risk of diabetes.
Hall et al. [148] 2008 1214 cross-sectional study Sleep duration is a significant correlate of the metabolic syndrome.
Facco et al. [163] 2010 189 During Pregnancy Short sleep duration was associated with glucose intolerance in pregnancy.
Qui et al. [153] 2010 1290 During Pregnancy The results suggest an association of short sleep duration with glucose intolerance and gestational diabetes.