Fig. (4) Schematic representation of the CEBPA mRNA translation mechanism, leading to the formation of the truncated or full-length C/EBPα protein. For truncated C/EBPα proteins, the translation starts at the uORF and stops after translation of the uORF. Then it reinitiates at AUG 3, generating the truncated isoform (A). For the generation of the full length C/EBPα the translation starts at the start codon AUG 1 or AUG 2 and reads trough (B). (Red: upstream open reading frame; Green: transactivation domain; Orange: DNA binding domain).