Table 4.: Trials Comparing Protein-Free and Protein-Containing Synthetic Surfactants

Year Authors Surfactants Used Participants Endpoints of Trial Results of Trial
2005 Moyes et al. [43]
  1. Colfosceril
  2. Lucinactant
 1036 ≤36 weeks GA
BW 600-1250g
  1. RDS rate
  2. BPD
  3. Mortality rate
 Lucinactant reduced RDS rate and BPD
No difference in mortality