Organisms | R. conorii[3] | C. burnetii [11] | C. burnetii [12] | F. tularensis[20] | F. tularensis[21] | F. tularensis[21] | B. anthracis[35] | B. anthracis[26] |
---|---|---|---|---|---|---|---|---|
Age (years) | 30 | 41 | 45 | 37 | 66 | 52 | 61 | 94 |
Gender | Male | Male | Male | Female | Male | Male | Female | Female |
Location | Greece | Northern Ireland | Spain | United States | Finland | Finland | United States | United States |
Occupation | Farmer | Bricklayer | Pharmaceuti-cal factory worker; spent weekends in the countryside | Landscaping | Gardener | Retired farmer | Central supply room hospital worker5 | N/A |
Medical history | Healthy | Healthy | Healthy | Healthy | Healthy | Tuberculosis 20 years ago | Hypertension | COPD, hypertension, chronic renal disease |
Clinical presentation | Headache, fever, chills, myalgia, dry cough, left pleuritic chest pain | Cough, left sided pleuritic chest pain, anorexia, weight loss | Acute fever, headaches, cough, asthenia, myalgia, arthralgia, weight loss, pleuritic pain | Fever, chills, pleuritic chest pain, myalgias, headache, night sweats, dry cough | Shortness of breath, chest pain, low-grade fever, abdominal pain | Fever, dyspnea | Weakness, chest heaviness, dyspnea, malaise, cough, chills | Fever, fatigue, myalgias, cough, shortness of breath |
Characterization of pleural effusion$$$ | Exudate | Exudate | Transudate | Exudate | Exudate | Exudate | Exudate | Exudate |
Radiographic manifestations | Left-sided pleural effusion | Left-sided pleural effusion | Bilateral pleural effusions | Left-sided pleural effusion with ipsilateral hilar adenopa-thy | Right- sided pleural effusion | Right lower lobe infiltrate and ipsilateral pleural effusion | Widened mediastinum, arge bilateral effusions, soft tissue edema | Widened mediastinum, bilateral effusions |
Pleural fluid analysis | ||||||||
Color | N/A | Straw | Sanguineous | Sanguineous | Serosanguineous | Serosanguineous | Serosanguineous | |
pH | 7.1 | 7.45 | N/A | N/A | N/A | N/A | 7.12 | |
TP (g/dL) | 5.6 | 5.5 | 5.2 | 5.0 | 4.7 | 4.2 | 3.4 | |
LDH (U/L) | 560 | N/A | 1080 | 573 | 584 | 1264 | 611 | |
Glucose (mg/dL) | 54 | N/A | 55 | 88.2 | 92 | 147 | 259.2 | |
Total nucleated cell count (per µL) | 1200 | 2,500 | 952 | 1,850 | 3000 | N/A | ||
Neutrophils (%) | 73 | 49 | N/A | N/A | N/A | N/A | ||
Lymph. (%) | 27 | 48 | 90.5 | 71 | N/A | N/A | ||
Eosinophils (%) | 70 | |||||||
Serum antibodies | 1:12481 | 1:1,2803 | 1:6404 | 1:6404 | ||||
IgM | 1:512 | 1:1922 | ||||||
IgG | 1:1024 | 1:2048 | ||||||
Pleural fluid culture | N/A | N/A | N/A | F. tularensis | F. tularensis | N/A | B. anthracis6 | B. anthracis6 |