| No. | Cell Type | Patent No. | Disease | Summary | Route of Administration | Refs. |
|---|---|---|---|---|---|---|
| 1 | Limbal Stem Cells | US20050080484A1 | De-epithelialized Cornea | Invention of corneal appliance is explained here. Wherein the lens body consists of endothelial cells procured from limbal stem cells. | Implantation to the target site. | [61] |
| 2 | Corneal endothelial cells | US20090222086A1 | Corneal endothelial defects and disorders | The invention provides a resolvable corneal button comprised of a biodegradable polymer which is capable of supporting the growth and expansion of endothelial cells on its surface for use in transplantation of healthy corneal endothelial cells to cornea tissue in need of a transplant and a method of using same. | Implantation to the target site. | [62] |
| 3 | Mesenchymal Stem Cells | CN104941001A | Ocular surface disorder like ophthalmology blinding corneal ulcers | In this patent, bone mesenchymal stem cells which are derived from allograft are planted on a silk protein biological film to develop the corneal patch used for curing corneal injuries; such as corneal ulcer. | Implantation to the target site. | [63] |
| 4 | Corneal stem cells, MSC or ESC | US20140072601A1 | Damaged or diseased ocular surface | The patent describes a hydrogel prepared encapsulating live cells like corneal stem cells, mesenchymal stem cells or embryonic stem cells. | Topical application at the target site. | [64] |
| 5 | Umbilical cord MSC | CN105147722A | Damaged or diseased ocular surface | This patent talks about a preparation containing sulphated Bletilla Striata polysaccharide and umbilical cord mesenchymal stem cells used for remarkably promoting the reproduction of corneal epithelial cells | Topical application at the target site. | [65] |
| 6 | Mesenchymal stem cell | CN107412266A | Conjunctival and Corneal ulcers | Invention of small pet eye drops made up of mesenchymal stem cells that can promote production of corneal epithelial cells on its application. | Eye drops applied at the target site. | [66] |
| 7 | Living endothelial cells | US20100274257A1 | Damaged or diseased ocular surface | This corneal endothelial tissue inserter associates to a medical device that works with eye tissue which retracts an extremely thin layer of donor endothelial eye tissue and places this tissue within the eye of a recipient. | Device acts like an Injection | [67] |