Inhibition of HIV-1 Replication by Secondary Metabolites From Endophytic Fungi of Desert Plants

Table 1.: Effect of Endophytic Compounds on HIV-1 Reverse Transcriptase

Compound	% RT Activity
DK	95 +/- 2
DL	100 +/- 10
DM	94 +/- 3
DP	100 +/- 1
DMSO	94 +/- 5
LAV	100 +/- 0
Mock	0 +/- 0

Inhibition of reverse transcriptase (RT) enzyme activity was determined by performing RT assays in the presence of the compounds DK, DM and DP at a concentration of 1.5 µg/mL, and DL at a concentration of 0.5 µg/mL. Controls for DMSO concentration present in compound wells (DMSO) and absence of compound (LAV) were included. A control with no virus present (mock) was also performed.